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Home >> Research >> Enrolling Now - Local Vasoconstriction in POTS

Local Vasoconstriction in Postural Tachycardia Syndrome (POTS)



We are seeking people with Postural Tachycardia Syndrome (POTS) ages 14-29 years of age to participate in a New York Medical College IRB-approved (L-7388-206A2), funded research protocol. The purpose is to investigate the ability to regulate local blood flow in patients with certain circulatory abnormalities. Some people can have symptoms such as dizziness, headache, fatigue, nausea, and palpitations when they are kept upright. This is called "orthostatic intolerance." When upright, some people may also develop high heart rates along with these symptoms. When this occurs, it is called postural tachycardia syndrome (POTS).

When you come for your testing, we will perform a type of tilt testing and other simple noninvasive tests. If you choose to participate, we will use a technique called intradermal microdialysis in which several tiny tubes are placed in the uppermost layer of the skin, while we simultaneously measure blood flow. Two 3mm biopsy samples will be obtained from the skin of your calf. In addition, we will also be administering Vitamin C through an IV placed in your arm and combine this with tilt-table testing, along with microneurography (MSNA). Muscle Sympathetic Nerve Activity (MSNA) involves an acupuncture like needle placed in a nerve behind your knee. Testing will take place over 4 days and you will be reimbursed $150 per day.

Further details of the research and representative consent forms can be found on our website, www.syncope.org.

If interested, please reply to:

Courtney Terilli, Research Coordinator
The Center for Hypotension
Department of Pediatrics
19 Bradhurst Avenue, Suite 1600 South
Hawthorne, New York 10532
courtney_terilli@nymc.edu; Telephone 914-593-8888

 

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